Aromatase Inhibitors for Men: Effects on Hormone Balance

Men with aromatase deficiency often develop osteopenia or osteoporosis, highlighting the enzyme’s role in bone health. Explore how aromatase inhibitors influence hormone balance in men, their mechanisms, types, and interactions with androgen therapy. Animal studies have demonstrated that supplemental calcium-d-glucarate reduces estradiol levels by as much as 25% 15. In the body, calcium D-glucarate serves as a slow-releasing reservoir of glucuronolactone, the latter of which appears to inhibit the actions of an enzyme called beta-glucuronidase. Likewise, men with low zinc levels consistently display lower androgen level readings, illustrating a definitive association between these two micronutrients and sex hormone levels.

First Things First – What Is an Aromatase Inhibitor?

Individuals with pre-existing health conditions, such as heart disease, should exercise caution and consult with their healthcare provider before using these inhibitors. Clinical outcomes were OS, castration resistance-free survival, time to a ≥ 50% decline (PSA50) and ≥ 90% decline (PSA90) in PSA from the latest baseline value, and time to undetectable PSA level (≤ 0.2 ng/mL). Patients without an event, or patients with no record of a medical visit for at least 12 months prior to study end (lost to follow-up) were censored at the last follow-up visit. OS, castration resistance-free survival, and time to PSA50, PSA90 and undetectable PSA were calculated from the index date to the date of the event.

Most people preferaromatase inhibitors due to their strong natural performance and fewer side effects compared to tamoxifen. The key benefits to look forward to with estrogen blockers include increased strength, greater endurance, and stronger muscle development. Customers report positive effects on estrogen levels, with one mentioning it helps even out hormones, while another notes it eliminates excessive estrogen and improves skin condition. Aromatase inhibitors have the potential to regulate energy balance and expenditure, making them an interesting avenue of research in obesity management. Lower estrogen levels, achieved with these inhibitors, can increase energy expenditure, potentially leading to weight loss. Androgen-deprivation therapy (ADT) was the standard of care for mCSPC for many decades5.

• Treatment with atamestane 100 mg once daily resulted in a 40% increase in total testosterone levels after 36 weeks.
• I usually assess testosterone and estradiol levels about one month after starting aromatase inhibitors.
• The unique set of chemicals called “alkalymides” in maca nourishes the endocrine system which is crucial in testosterone production.

DIM: Is It Really An Aromatase Inhibitor?

It’s important to note that the use of estrogen blockers should be under the supervision of a qualified healthcare provider to ensure proper dosage and safety. Chrysin Plus DIM Aromatase Inhibitor Cream is a natural supplement that supports healthy hormone balance in men and women. This cream contains Chrysin and DIM, which work together as aromatase inhibitors to reduce excess estrogen in the body.

Some bodybuilders take Arimidex to reduce the side effects of anabolic steroids. The drug is a breast cancer treatment that lowers estrogen levels, so a person should avoid using Boldenon 250 mg RB Pharma it for other means. Arimidex does not lower testosterone but instead is known to increase testosterone levels while decreasing estrogen levels potentially. This is why the drug is sometimes used to treat low testosterone in men in place of hormone replacement therapy, usually where lowered testosterone is caused by aging.